India: Findings to lead in fight against inflammatory infections: Prof Abhay

IIT Kanpur

Kanpur: Both IIT Kanpur and the University of Queensland (UQ) have worked together on path-breaking global research in chronic inflammatory disease.

A protein receptor, C5aR2, plays a vital role in the moderation of many immune and inflammatory processes and explores its use as a potential therapeutic target for treating multiple chronic inflammatory diseases. 

Prof Arun Shukla, IIT Kanpur, India with researchers Asuka Inoue, Tohoku University, Japan and Stéphane A Laporte, McGill University, Canada worked on the research.

This is the first time that researchers have identified key molecules within the immune system that may help fight the inflammation that drives chronic inflammatory diseases.

The findings of the research will help study in novel drug molecules that can act on the receptors for C5a, a potent immune molecule. 

It is linked to multiple immune-linked inflammatory diseases such as cancer, rheumatoid arthritis, sepsis and even Covid-19.

Prof. Abhay Karandikar, Director, IIT Kanpur said "The publication of the research paper on inflammatory diseases is testament to the capabilities of IIT Kanpur to undertake challenging research at the frontiers of science."

"We are optimistic that the findings will lead to new light in the fight against chronic inflammatory diseases," he said.